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Updated: Jun 10, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
[History of implant-free anterior cruciate ligament reconstruction]
1Atos-Klinik, Bismarckstr. 9, 69115, Heidelberg, Deutschland. hans.paessler@atos.de
Abstract:
Most recent articles on anterior cruciate ligament (ACL) reconstruction focus on anatomic tunnel placement, but reviewing the early history of ACL reconstruction it can be seen that at the beginning of the 20th century Ernest Hey-Groves had already pointed out the importance of anatomic placement of the tunnels. Palmer even developed a femoral drill guide for precise anatomic placing of the tunnel before World War II. The possibility of graft fixation without any fixation material is also not new and was described as early as 1967 by Brückner from Rostock. Many techniques in ACL reconstruction with non-anatomic placement and high failure rates could have been avoided if surgeons had been aware of what the early pioneers in this important field of orthopedic surgery had already described.