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In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Viability assessment by multidetector computed tomography in Takotsubo cardiomyopathy
Jamal Hussain1, Aslan Ghandforoush, Zahid Virk
1Department of Cardiology, Banner Good Samaritan Medical Center, Phoenix, AZ, USA. xnorbeht@yahoo.com
Insights
Takotsubo cardiomyopathy, a stress-induced heart condition, was evaluated using multidetector computed tomography (MDCT). MDCT imaging revealed no delayed hyperenhancement, indicating its utility in diagnosing this condition.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Takotsubo cardiomyopathy, or stress-induced cardiomyopathy, is a recognized syndrome of transient cardiac dysfunction.
- It mimics myocardial infarction but occurs without significant coronary artery disease, likely due to catecholamine overload.
Observation:
- Multidetector computed tomography (MDCT) is a rapid, noninvasive imaging technique for assessing coronary anatomy and cardiac function.
- MDCT's utility in evaluating myocardial viability after infarction is less reported.
Findings:
- This report details the MDCT imaging of two patients diagnosed with Takotsubo cardiomyopathy.
- For the first time, MDCT demonstrated the absence of delayed hyperenhancement in these patients.
Implications:
- MDCT can be a valuable tool in the diagnostic workup of Takotsubo cardiomyopathy.
- The absence of delayed hyperenhancement on MDCT helps differentiate Takotsubo cardiomyopathy from myocardial infarction.
Abstract:
Stress-induced cardiomyopathy, known as Takotsubo, is an increasingly recognized syndrome, characterized by transient apical or midventricular dysfunction, which mimics myocardial infarction in the absence of significant coronary artery disease, and is thought to be due to transient catecholamine overload. Multidetector computed tomography (MDCT) is a novel imaging approach increasingly recognized as a rapid, noninvasive diagnostic modality to assess coronary anatomy and cardiac function. Few reports have been published regarding its utility in the assessment of myocardial viability after myocardial infarction. We describe 2 patients with Takotsubo cardiomyopathy who underwent MDCT imaging. To our knowledge, this is the first report describing the utility of MDCT that shows the absence of delayed hyperenhancement in patients with Takotsubo cardiomyopathy.
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