Related Experiment Video
Updated: Jun 10, 2026

Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
Published on: May 9, 2022
[The effect of periodontal initial therapy on chronic periodontitis and subgingival periodontal pathogen]
Rong Shu1, Zhong-chen Song, Lin-hua Ge
1Department of Periodontology, College of Stomatology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai 200011, China. shurong123@hotmail.com
Purpose:
To evaluate the effect of periodontal initial therapy on clinical parameters and subgingival periodontal pathogen in patients with chronic periodontitis.
Methods:
One hundred and twenty patients with chronic periodontitis were included. Probing depth (PD), attachment loss (AL), plaque index (PLI) and gingival index (GI) were evaluated at baseline and after-initial therapy. P.g and A.a in subgingival plaque were investigated by real-time PCR. Data was statistically analyzed by SAS6.12 software for Student's t test.
Results:
The PD, AL, PLI and GI were significantly decreased after periodontal initial therapy (P<0.01), and meanwhile the ratio of P.g versus total bacteria was significantly decreased after-initial therapy (P<0.05). However, the change of ratio of A.a versus total bacteria was not significant (P>0.05).
Conclusion:
Periodontal initial therapy could effectively control the inflammation of chronic periodontitis, and decrease the ratio of P.g in subgingival plaque.
Related Concept Videos
The Oral Microbiota
Development of the Oral Microbiota