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Vitamin D levels in children undergoing adenotonsillectomies
Rania Esteitie1, Robert M Naclerio, Fuad M Baroody
1Section of Otolaryngology-Head and Neck Surgery, The University of Chicago Medical Center and The Pritzker School of Medicine, The University of Chicago, Chicago, IL, USA.
Insights
This study found no link between vitamin D levels and the need for adenotonsillectomy (T&A) in children. However, African American children had lower vitamin D levels than Caucasian children.
Area of Science:
- Pediatric Otolaryngology
- Endocrinology
- Immunology
Background:
- Emerging evidence suggests vitamin D plays a role in immune system regulation.
- Adenotonsillectomy (T&A) is a common surgical procedure in children.
- Understanding factors influencing T&A is crucial for pediatric health.
Purpose of the Study:
- To investigate serum vitamin D levels in children undergoing adenotonsillectomy (T&A).
- To compare vitamin D levels between children needing T&A and a control group.
- To explore potential correlations between vitamin D and disease parameters in children undergoing T&A.
Main Methods:
- Prospective data collection from 47 children undergoing T&A and 15 controls at a tertiary care children's hospital.
- Measurement of serum 25-hydroxy (OH)-vitamin D levels.
- Collection of demographic and disease-specific data.
Main Results:
- No significant differences in vitamin D levels were observed between children undergoing T&A and control groups.
- Vitamin D levels did not correlate with any disease parameters in children undergoing T&A.
- African American children exhibited significantly lower vitamin D levels compared to Caucasian children.
Conclusions:
- This pilot study did not establish an association between serum vitamin D levels and the indication for adenotonsillectomy (T&A).
- Race was identified as a factor associated with vitamin D levels in the studied pediatric population.
Objective:
Because of the recent data supporting an immunoregulatory role for vitamin D, we evaluated levels of vitamin D in children undergoing adenotonsillectomies (T&A) and controls.
Methods:
We prospectively collected data from 47 children undergoing T&As and 15 undergoing unrelated elective procedures at a tertiary care children's hospital. Demographic and disease specific data was obtained in addition to a blood sample for the measurement of 25-hydroxy (OH)-vitamin D.
Results:
There were no differences in vitamin D levels between the groups and levels did not correlate to any disease parameters in the children undergoing T&A. The only significant differences were related to race in that African American children had significantly lower vitamin D levels compared to Caucasians.
Conclusion:
This pilot study did not show an association between serum vitamin D and the need to have adenotonsillectomy.
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