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The novel function of advanced glycation end products in regulation of MMP-9 production

Fan Zhang1, Greg Banker, Xiaodong Liu

  • 1Department of Surgery, Division of Vascular Surgery, University of Wisconsin School of Medicine, Madison, Wisconsin 53705, USA.

Abstract

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Overview
In order to maintain tissue organization, many animal cells are surrounded by structural molecules that make up the extracellular matrix (ECM). Together, the molecules in the ECM maintain the structural integrity of tissue as well as the remarkable specific properties of certain tissues.
Composition of the Extracellular Matrix
The extracellular matrix (ECM) is commonly composed of ground substance, a gel-like fluid, fibrous components, and many structurally and functionally diverse...