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Related Experiment Video

Updated: Jun 10, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

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Published on: December 11, 2017

Improving left ventricular pacing threshold using retained guidewire technique: a case report.

Fu Yi¹, Min Shen, Feng Wu

¹Department of Cardiovascular Medicine, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi 710032, China.

Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology

|July 20, 2010

Summary

Cardiac resynchronization therapy (CRT) implantation, particularly the left ventricular lead, is complex. A novel guidewire technique significantly lowered LV lead pacing thresholds, showing stable results at 12 months.

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Last Updated: Jun 10, 2026

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Published on: January 31, 2019

Area of Science:

Cardiology
Medical Devices
Electrophysiology

Background:

Cardiac resynchronization therapy (CRT) is a key treatment for heart failure.
Left ventricular (LV) lead implantation complexity hinders widespread CRT adoption.

Observation:

A specific pacing lead guidewire was utilized during LV lead implantation.
This technique aimed to simplify the implantation procedure and improve lead performance.

Findings:

The guidewire use led to a significant reduction in the LV lead's pacing threshold.
This reduced pacing threshold remained stable over a 12-month follow-up period.

Implications:

This technique may offer a solution to reduce LV lead pacing thresholds.
Simplifying CRT implantation could enhance patient access to this therapy.
Stable low pacing thresholds are crucial for long-term CRT efficacy.