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Familial dermographism.

K B Jedele¹, V V Michels

¹Department of Medical Genetics, Mayo Clinic, Rochester, MN 55905.

American Journal of Medical Genetics

|May 1, 1991

Summary

This summary is machine-generated.

Familial dermographism, a skin reaction to scratching, may be inherited. This study presents a four-generation family with this rare condition, discussing its genetic basis and other familial physical urticarias.

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Area of Science:

Dermatology
Genetics

Background:

Urticaria can be triggered by physical stimuli, presenting in sporadic or familial forms.
Dermographism, characterized by skin reactions to stroking, is the most common physical urticaria.

Observation:

A four-generation family exhibiting dermographism was identified.
This presentation suggests a potential hereditary pattern for dermographism, previously unreported.

Findings:

Dermographism in this family appears to be inherited as an autosomal dominant trait.
The study discusses sporadic dermographism and other familial physical urticarias.

Implications:

This research highlights the possibility of genetic inheritance in dermographism.

Understanding familial physical urticarias can aid in diagnosis and management.