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Related Experiment Video

Updated: Jun 10, 2026

Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care

Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care

Published on: May 10, 2024

The microcirculation in sepsis.

Asha Tyagi¹, Ashok Kumar Sethi, Gautam Girotra

¹Reader, Department of Anaesthesiology & Critical Care, University College of Medical Sciences & Guru Teg Bahadur Hospital, Shahadra, Delhi-110095, India.

Indian Journal of Anaesthesia

|July 20, 2010

Summary

This summary is machine-generated.

Sepsis critically impacts critically ill patients. This review highlights the microcirculation

Keywords:

Micro-haemodynamics Microcirculation Sepsis

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Last Updated: Jun 10, 2026

Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care

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Published on: May 10, 2024

Real-Time Assessment of Spinal Cord Microperfusion in a Porcine Model of Ischemia/Reperfusion

Real-Time Assessment of Spinal Cord Microperfusion in a Porcine Model of Ischemia/Reperfusion

Published on: December 10, 2020

Area of Science:

Critical care medicine
Physiology
Pathophysiology

Background:

Sepsis is a major cause of death in intensive care units.
Sepsis involves complex systemic responses including inflammation and coagulation.
The role of microcirculation in sepsis is increasingly recognized.

Purpose of the Study:

To review the importance of microcirculation in sepsis.
To discuss methods for assessing microcirculation.
To explore therapies for improving microcirculation in sepsis.

Main Methods:

Literature review of sepsis pathophysiology and microcirculation.
Analysis of current assessment techniques for microcirculation.
Synthesis of therapeutic strategies targeting microcirculation.

Main Results:

Microcirculation dysfunction is a key feature of sepsis.
Various techniques exist to evaluate microcirculatory parameters.
Therapeutic interventions can potentially restore microcirculatory function.

Conclusions:

Understanding and targeting microcirculation is crucial for sepsis management.
A shift from macrohemodynamics to microhemodynamics is needed.
Further research into microcirculatory resuscitation in sepsis is warranted.