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Postoperative Analgesia in Children- Comparative Study between Caudal Bupivacaine and Bupivacaine plus Tramadol
Meena Doda1, Sambrita Mukherjee
1Specialist & HOD, Dept.of Anaesthesiology, ESIC Hospital, Noida, India- 201301.
Insights
Adding tramadol to caudal bupivacaine significantly extends postoperative pain relief in children undergoing surgery. This combination provides longer analgesia without notable adverse effects, improving pain management in pediatric patients.
Area of Science:
- Pediatric Anesthesiology
- Pain Management
- Pharmacology
Background:
- Effective postoperative pain management is crucial for pediatric surgical patients.
- Caudal block with bupivacaine is a common analgesic technique.
- Optimizing the duration and efficacy of analgesia is an ongoing clinical challenge.
Purpose of the Study:
- To evaluate the efficacy of adding tramadol to caudal bupivacaine for postoperative analgesia in children.
- To compare the duration of analgesia between bupivacaine alone and bupivacaine-tramadol combination.
Main Methods:
- A double-blind study involving 30 children (2-5 years) undergoing subumbilical surgery.
- Randomized groups: Group A (bupivacaine) and Group B (bupivacaine + tramadol).
- Postoperative pain assessed using the Toddler-Preschool Postoperative Pain Scale (TPPPS).
Main Results:
- The mean duration to the first analgesic dose was significantly longer in the tramadol group (9.1 hours) compared to the bupivacaine-only group (6.3 hours) (p<0.01).
- No significant differences in hemodynamic changes, motor weakness, or respiratory depression were observed between groups.
- Tramadol addition enhanced the analgesic duration of caudal bupivacaine.
Conclusions:
- Combining tramadol with caudal bupivacaine provides prolonged postoperative analgesia in pediatric patients.
- This combination is safe and effective, with no significant increase in adverse effects.
- Tramadol is a valuable adjunct to caudal bupivacaine for pediatric pain management.
Summary:
Thirty children, ASAI-II, aged between 2yrs-5yrs, undergoing sub umbilical operation (inguinal and penile surgery) were selected for this double blind study. They were randomly divided in two groups, group A and group B. Group A(n=15) received 0.25%bupivacaine 0.5ml.kg(-1) and Group B (n=15) received 0.25% bupivaeaine 0.5ml.kg(-1) and tramadol 2mg.kg(-1) as single shot caudal block. Postoperative pain was assessed by a modified TPPPS (Toddler-Preschool Postoperative Pain Scale) and analgesic given only when the score was more than 3. In the first 24 hrs it was observed that the mean duration of time interval between the caudal block and first dose of analgesic was significantly long(9.1hrs) in Group B as compared to Group A (6.3hrs) which was much shorter(p<0.01). There was no significant haemodynamie changes, motor weakness or respiratory depression in both groups. This study concluded that addition of tramadol 2mg.kg(-1) to caudal 0.25% bupivacaine 0.5ml.kg(-1) significantly prolong the duration of postoperative analgesia in children without producing much adverse effects.
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