Related Experiment Video
Updated: Jun 10, 2026
05:12
Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
Published on: May 12, 2023
Total parathyroidectomy without autotransplantation for renal hyperparathyroidism
J E Coulston1, R Egan, E Willis
1Department of Endocrine Surgery, North Bristol NHS Trust, Bristol, UK. jamescoulston@yahoo.co.uk
The British Journal of Surgery
|July 20, 2010
Summary
Total parathyroidectomy alone is a safe and effective treatment for renal hyperparathyroidism, showing minimal complications and a low recurrence rate in medium- to long-term follow-up.
Area of Science:
- Endocrinology
- Surgical Oncology
- Nephrology
Background:
- Parathyroidectomy is the standard treatment for renal hyperparathyroidism.
- Controversy exists regarding the optimal surgical procedure.
- Total parathyroidectomy without autotransplantation or thymectomy is a potential approach.
Purpose of the Study:
- To review the medium- to long-term results of total parathyroidectomy without autotransplantation or thymectomy for renal hyperparathyroidism.
Main Methods:
- Retrospective review of 115 patients undergoing total parathyroidectomy between August 2000 and March 2009.
- Procedure performed by a single surgeon.
- Median follow-up of 31 months.
Main Results:
- No re-explorations for bleeding or recurrent laryngeal nerve injuries.
- Postoperative hypocalcemia rate: 15.7%.
- Recurrent hyperparathyroidism rate: 12.2% with a median PTH of 35.4 pmol/l.
- Reoperation rate: 3.5%.
Conclusions:
- Total parathyroidectomy alone demonstrates minimal morbidity and mortality.
- The procedure offers good medium- to long-term clinical outcomes.
- A low recurrence rate is associated with this surgical approach.
Related Concept Videos
01:26Kidney Transplant II: Surgical Procedure
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
00:59The Parathyroid Glands
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by producing...
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by producing...
01:28Kidney Transplant I: Introduction
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...