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Giant cell tumours in hand bones.

Muhammad Saeed Minhas¹, Ghulam Mehboob, Irfanullah Ansari

¹Department of Orthopaedics, Jinnah Postgraduate Medical Centre, Karachi, Pakistan. drminhas@hotmail.com

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

|July 21, 2010

Summary

This summary is machine-generated.

Giant cell tumour (GCT) of the hand is a rare, aggressive bone tumor. Surgical resection with reconstruction or amputation is the recommended treatment, showing good outcomes.

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Area of Science:

Orthopedic Oncology
Skeletal Tumors
Hand Surgery

Background:

Giant cell tumour (GCT) is a primary bone neoplasm.
GCT of the hand is exceptionally rare, comprising a small percentage of all GCT cases.
Understanding the specific characteristics of GCT in the hand is crucial for effective management.

Purpose of the Study:

To delineate the clinical, radiological, and surgical aspects of GCT in the hand.
To evaluate the aggressiveness, multicentricity, and staging of hand GCT at presentation.
To assess treatment outcomes and recurrence rates for GCT of the hand.

Main Methods:

A retrospective case series design was employed.
Data were collected from January 1990 to January 2009 at Jinnah Postgraduate Medical Centre, Karachi.
Seven cases of GCT of the hand bones were analyzed for clinical and radiographic features, surgical procedures, and follow-up outcomes.

Main Results:

GCT of the hand accounted for 3.3% of all GCTs (7 out of 210 cases).
The average age of affected patients was 24.28 years, with a slight male predominance (57%).
All cases presented as radiological stage 3, with one instance of multicentricity; surgical management involved excision with reconstruction or ray amputation, with no reported complications or recurrences during follow-up (average 4.5 years).

Conclusions:

Giant cell tumour of the hand is a rare entity with distinct clinical and radiographic presentations.
It exhibits aggressive behavior, often involving the entire bone early, and can present as multicentric.
Surgical resection with reconstruction or ray amputation is the preferred treatment, yielding favorable outcomes.