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Updated: Jun 10, 2026

Preparation and Implantation of Electrodes for Electrically Kindling VGAT-Cre Mice to Generate a Model for Temporal Lobe Epilepsy
Published on: August 17, 2021
Refractory nonconvulsive status epilepticus in Creutzfeldt-Jakob disease
Maria Aiguabella1, Mercè Falip, Misericordia Veciana
1Neurology Department, Hospital de Bellvitge, Hospitalet de Llobregat, Barcelona, Spain. 37785mam@comb.cat
Abstract:
Creutzfeldt-Jakob disease (CJD) is a rare human transmissible spongiform subacute encephalopathy. The most common clinical manifestations of CJD include rapidly progressive dementia, behavioural changes, cerebellar dysfunction and myoclonus. Other seizure types are rare and nonconvulsive status epilepticus (SE) is exceptional. We report a case of a 44-year-old man who presented a psychotic episode followed by akinetic mutism and refractory nonconvulsive SE. The final diagnosis was CJD. Continuous video-EEG monitoring revealed the ictal pattern of nonconvulsive SE to be periodic sharp wave complexes characteristic of CJD. [Published with video sequences].
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