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Cerebral miliary micro aneurysms in polyarteritis nodosa: report of two cases

Sandeep Sharma1, Subhash Kumar, N K Mishra

  • 1Department of Neuroradiology, AIIMS, New Delhi, India. drsharma_sandeep@yahoo.com

Neurology India
|July 21, 2010
PubMed

Insights

Polyarteritis nodosa (PAN) rarely affects the brain, but multiple intracranial aneurysms can occur. Cerebral angiography is recommended during abdominal angiograms for PAN patients to detect these potentially asymptomatic aneurysms.

Area of Science:

  • Neurology
  • Vascular Inflammation
  • Radiology

Background:

  • Polyarteritis nodosa (PAN) is a systemic vasculitis.
  • Cerebral involvement in PAN is uncommon, typically presenting as ischemic events or hemorrhages.
  • Intracranial aneurysms secondary to PAN are considered extremely rare.

Observation:

  • This report details two cases of PAN patients with multiple intracranial aneurysms.
  • One patient experienced an intracerebral hemorrhage.
  • The second patient's multiple intracranial aneurysms were asymptomatic incidental findings.

Findings:

  • The findings suggest that multiple intracranial aneurysms may be more common in PAN than previously thought.
  • These aneurysms can be present even without neurological symptoms.

Implications:

  • Cerebral angiography should be considered during abdominal angiograms in patients diagnosed with PAN.
  • Early detection of intracranial aneurysms in PAN patients can potentially prevent severe neurological complications.
  • This highlights the importance of comprehensive vascular assessment in PAN management.

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