Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been developed.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dynamic visualization of physiological CaMKII activity using sensitive FRET biosensors.

bioRxiv : the preprint server for biology·2026
Same author

GPR3 Ligands Discovered through Combined Virtual and Conformational Biosensor-Based Screening.

Journal of the American Chemical Society·2026
Same author

Ligand-specific activation trajectories dictate GPCR signalling in cells.

Nature·2026
Same author

MRAP2 modifies the signaling and oligomerization state of the melanocortin-4 receptor.

Nature communications·2025
Same author

Disruption of constitutive CXCR4 oligomers impairs oncogenic properties in lymphoid neoplasms.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Pharmacological characterization of a clinical candidate, TG-0054, a small molecule inverse agonist targeting CXCR4.

Molecular pharmacology·2025
Same journal

Cryo-EM sheds light on the mechanism of human telomerase inhibition by BIBR1532.

Nature chemical biology·2026
Same journal

Artificial metalloenzymes in complex biological environments.

Nature chemical biology·2026
Same journal

Allosteric disordering of eIF2B regulates the integrated stress response.

Nature chemical biology·2026
Same journal

A tail of two ligases.

Nature chemical biology·2026
Same journal

Non-canonical cytochrome P450 enzymes expand the diversity of bacterial hemoproteins.

Nature chemical biology·2026
Same journal

Image-guided activation of drugs with electromagnetic radiation.

Nature chemical biology·2026
See all related articles

Related Experiment Video

Updated: Jun 10, 2026

Visualizing Clathrin-mediated Endocytosis of G Protein-coupled Receptors at Single-event Resolution via TIRF Microscopy
12:40

Visualizing Clathrin-mediated Endocytosis of G Protein-coupled Receptors at Single-event Resolution via TIRF Microscopy

Published on: October 20, 2014

Microscopy: GPCR dimers moving closer

Manuela Ambrosio, Martin J Lohse

    Nature Chemical Biology
    |July 21, 2010
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Imaging G-protein Coupled Receptor (GPCR)-mediated Signaling Events that Control Chemotaxis of Dictyostelium Discoideum
    09:40

    Imaging G-protein Coupled Receptor (GPCR)-mediated Signaling Events that Control Chemotaxis of Dictyostelium Discoideum

    Published on: September 20, 2011

    Photoactivated Localization Microscopy with Bimolecular Fluorescence Complementation (BiFC-PALM)
    12:42

    Photoactivated Localization Microscopy with Bimolecular Fluorescence Complementation (BiFC-PALM)

    Published on: December 22, 2015

    Related Experiment Videos

    Last Updated: Jun 10, 2026

    Visualizing Clathrin-mediated Endocytosis of G Protein-coupled Receptors at Single-event Resolution via TIRF Microscopy
    12:40

    Visualizing Clathrin-mediated Endocytosis of G Protein-coupled Receptors at Single-event Resolution via TIRF Microscopy

    Published on: October 20, 2014

    Imaging G-protein Coupled Receptor (GPCR)-mediated Signaling Events that Control Chemotaxis of Dictyostelium Discoideum
    09:40

    Imaging G-protein Coupled Receptor (GPCR)-mediated Signaling Events that Control Chemotaxis of Dictyostelium Discoideum

    Published on: September 20, 2011

    Photoactivated Localization Microscopy with Bimolecular Fluorescence Complementation (BiFC-PALM)
    12:42

    Photoactivated Localization Microscopy with Bimolecular Fluorescence Complementation (BiFC-PALM)

    Published on: December 22, 2015