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Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
Published on: February 23, 2017
An organic matrix-mediated processing methodology to fabricate hydroxyapatite based nanostructured biocomposites
Prakash Hariram Kithva1, Lisbeth Grøndahl, Rajendra Kumar
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, 4072, Australia.
Nanoscale
|July 21, 2010
Summary
Researchers developed nanostructured composite films using amorphous calcium phosphate and polymer solutions. These films transform into crystalline hydroxyapatite, showing potential for advanced material applications.
Area of Science:
- Materials Science
- Biomaterials Engineering
- Nanotechnology
Background:
- Amorphous calcium phosphate (ACP) is a precursor for hydroxyapatite (HAp) formation.
- ACP can be synthesized by reacting orthophosphoric acid with calcium hydroxide.
- Polymer-assisted synthesis offers routes to control material structure and properties.
Purpose of the Study:
- To investigate the transformation of ACP into crystalline HAp using polymer solutions.
- To fabricate nanostructured composite films via solvent casting.
- To characterize the structural and mechanical properties of the resulting films.
Main Methods:
- Synthesis of an amorphous calcium phosphate precursor phase.
- Introduction of polymer solutions to induce transformation to crystalline hydroxyapatite.
- Solvent casting technique for forming concentrated hybrid suspensions.
- Characterization of film structure and mechanical properties.
Main Results:
- Successful transformation of amorphous calcium phosphate to crystalline hydroxyapatite was achieved by incorporating polymer solutions.
- Nanostructured composite films were fabricated using a solvent casting method.
- The structural and mechanical properties of the hydroxyapatite-based composite films were evaluated.
Conclusions:
- Polymer-assisted transformation provides a viable method for synthesizing crystalline hydroxyapatite.
- Solvent casting is effective for producing nanostructured composite films from hybrid suspensions.
- The characterized films exhibit properties suitable for potential applications in biomaterials or nanotechnology.
