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[Colonic angiodysplasia with chronic digestive hemorrhage cured after valvular replacement for aortic valve stenosis]
J F Obadia1, A Brachet, J P Lancon
1Service de chirurgie cardiovasculaire et angiologie, hôpital du Bocage, Dijon.
Insights
Aortic stenosis and gastrointestinal angiodysplasia bleeding can be managed by prioritizing aortic valve replacement. This cardiac surgery often resolves bleeding, making subsequent gastrointestinal interventions unnecessary.
Area of Science:
- Cardiology
- Gastroenterology
- Vascular Medicine
Background:
- Aortic stenosis is present in 15-25% of patients with gastrointestinal angiodysplasia.
- Standard treatments for bleeding angiodysplasia include resection and coagulation, but these are often ineffective when associated with aortic stenosis.
Observation:
- A 73-year-old woman with chronic anemia and GI bleeding, initially attributed to portal hypertension, underwent multiple ineffective surgeries.
- She was later diagnosed with gram-negative endocarditis complicating aortic stenosis and mitral regurgitation.
Findings:
- Following successful double valve replacement surgery for aortic stenosis and mitral regurgitation, the patient experienced complete resolution of gastrointestinal bleeding.
- Three years post-surgery, colonoscopies remained normal, indicating sustained remission of angiodysplasia-related hemorrhage.
Implications:
- In cases of concurrent severe valvular heart disease and angiodysplasia, valve surgery should be the primary intervention.
- Gastrointestinal surgery for bleeding angiodysplasia is reserved for cases where bleeding persists after cardiac intervention.
Abstract:
Aortic stenosis is found in 15 to 25% of patients with gastrointestinal angiodysplasia. The usual treatment for haemorrhagic angiodysplasia associated with aortic stenosis is the same as for other types of gastrointestinal angiodysplasias: segmental intestinal resection, electrocoagulation and laser photocoagulation. The authors report the case of a 73 year old woman with a long history of gastro-intestinal bleeding and chronic anaemia requiring a number of hospital admissions for blood transfusions. The cause of this bleeding remained obscure for many years, as it was initially thought to be due to portal hypertension complicating cyrrhosis and a surgical porto-caval shunt was performed. Later, angiodysplasia of the colon was recognised and a segmental colonic resection was performed. These two surgical procedures had no effect on the chronic bleeding and finally the patient was referred for a gram negative endocarditis complicating aortic stenosis, previously considered to be non-surgical. After controlling the infection, the patient was sent for surgery of the aortic valve disease with mitral regurgitation in view of progressive degradation of left ventricular function. A double valve replacement with bioprostheses was undertaken with no complication. Finally, three years now after valve replacement, no further bleeding has occurred and control colonoscopy is normal. In the light of this case and a review of the literature of about 30 similar cases, the physiopathology and management of these patients is discussed with respect to the choice of valve prosthesis and the attitude to anticoagulant therapy. These observations suggest that in the presence of valvular heart disease at a surgical stage associated to an angiodysplasia, it is preferable to propose valve surgery to start with. Gastro-intestinal surgery is only indicated if haemorrhage persists after a period of observation.