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Updated: Jun 10, 2026

Adoptive Immunotherapy of iNKT Cells in Glucose-6-Phosphate Isomerase (G6PI)-Induced RA Mice
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Adoptive Immunotherapy of iNKT Cells in Glucose-6-Phosphate Isomerase (G6PI)-Induced RA Mice

Published on: January 31, 2020

Rapid improvement of pyoderma gangrenosum after treatment with infliximab

Joanna L Chan1, Michael S Graves, Clay J Cockerell

  • 1Department of Dermatology, University of Texas Southwestern Medical Center, Dallas,TX 75390-9069, USA. docjochan@gmail.com

Journal of Drugs in Dermatology : JDD
|July 22, 2010
PubMed

Infliximab, a novel chimeric anti-tumor necrosis factor-alpha (TNF-alpha) monoclonal antibody, has been increasingly used in the treatment of pyoderma gangrenosum. However, an established dosing regimen is lacking in the published literature. A variety of dosing regimens have been suggested, including a treatment schedule similar to that of psoriasis. The authors report a case of rapid response to infliximab in a patient with pyoderma gangrenosum associated with inflammatory bowel disease utilizing a dosing regimen similar to that used for psoriasis.

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