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Rapid Genetic Analysis of Epithelial-Mesenchymal Signaling During Hair Regeneration
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Published on: February 28, 2013

Follicular bisection in hair restoration: in vivo experiment

Alfredo Rossi1, Michele Gilio, Giuseppe Pistola

  • 1Department of Skin-Venereal Disease and Reconstructive and Plastic Surgery, Sapienza University of Rome, Rome, Italy. alfredo.rossi@uniroma1.it

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]
|July 22, 2010
PubMed
Abstract

No abstract available in PubMed .

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A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...

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