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Published on: July 25, 2019
[CT-research about how to design the diameter and length of the modular branched stent-graft]
Xin Du1, Wei Guo, Xiao-ping Liu
1Department of Vascular Surgery, People's Liberation Army General Hospital, Beijing, China.
Insights
This study measured the anatomical dimensions of the ascending aorta and aortic arch in the Chinese population using CT scans. Findings provide crucial data for tailoring medical devices like stent-grafts to this demographic.
Area of Science:
- Cardiovascular Anatomy
- Medical Imaging
- Population Studies
Background:
- Accurate anatomical data of the aorta is essential for cardiovascular interventions.
- Previous studies may not fully represent the Chinese population's aortic dimensions.
Purpose of the Study:
- To characterize the anatomical features of the ascending aorta and aortic arch in a Chinese cohort.
- To provide foundational data for the design and application of aortic stent-grafts.
Main Methods:
- Thoracic aorta CT angiography (CTA) was performed on 388 patients without known aortic pathology.
- Measurements of the ascending aorta, aortic arch, and branch vessels were systematically recorded.
- Statistical analysis was conducted using CHISS software.
Main Results:
- Detailed measurements of aortic diameters at various key levels (e.g., above coronary artery, origin of brachiocephalic trunk) were established.
- Aortic lumen lengths and distances between major branch vessels were quantified.
- Normative data for ascending aorta and aortic arch dimensions in the Chinese population were generated.
Conclusions:
- The anatomical data supports the suitability of modular branched stent-graft systems for the Chinese population.
- These findings enable the selection of appropriate stent-graft sizes for individuals.
Objective:
To study the anatomical characteristics about ascending aortic and aortic arch in Chinese population by CT.
Methods:
From September 2006 to September 2007, 388 patients free of current known aortic pathology undergone thoracic aorta CTA. The diameter of ascending aorta, aortic arch, and branch vessels of aortic arch were measured respectively by AW4.2 work station. The data base about all the measurements was set up. The CHISS statistical software was used to analysis data.
Results:
The aortic diameter above coronary artery (CA), the level at origin of and brachiocephalic trunk (BCT), the halfway of the ascending aorta, the level at origin of left common carotid artery (LCCA), the level at origin of left subclavian artery (LSA) and the level at distal of origin of LSA respectively were (34 +/- 5) mm, (34 +/- 5) mm, (33 +/- 4) mm, (30 +/- 4) mm, (28 +/- 3) mm and (26 +/- 3) mm. The diameters of two level between the origin of BCT and right subclavian artery (RSA) were (13.1 +/- 1.9) mm and (12.8 +/- 2.3) mm. Diameters of two level at LCCA were (8.7 +/- 1.5) mm and (7.9 +/- 1.0) mm. The diameters of two level between the origin of LSA and left vertebral artery were (10.7 +/- 1.7) mm and (9.3 +/- 1.3) mm. The aortic lumina length between the origin of CA and BCT was (5.3 +/- 1.2) cm, the aortic lumina length between the origin of BCT and LCCA was (1.3 +/- 0.4) cm, the lumen length between origin of BCT and RSA was (4.1 +/- 0.8) cm, the lumen length between origin of LSA and left vertebral artery was (3.8 +/- 0.8) cm. The distance between the wall of BCT and LCCA was (0.4 +/- 0.2) cm, the distance between the wall of LCCA and LSA was (0.7 +/- 0.6) cm.
Conclusions:
Modular branched stent-graft system is fit for most part of the Chinese. The size fit for human could be got on this basic.
