Related Experiment Video
Updated: Jun 10, 2026

Positron Emission Tomography-based Dose Painting Radiation Therapy in a Glioblastoma Rat Model using the Small Animal Radiation Research Platform
Published on: March 24, 2022
Quantitative and analytical comparison of isodose distributions for shaped electron fields from ADAC Pinnacle
E Ishmael Parsai1, Diana Shvydka, Jun Kang
1University of Toledo Health Science Campus, Department of Radiation Oncology, Mail Stop 1151, 3000 Arlington Avenue, Toledo, OH 43614, USA. e.parsai@utoledo.edu
Abstract:
We assess the accuracy of ADAC Pinnacle(3) commercial treatment planning system (TPS) in computation of isodose distributions for shaped electron fields. The assessment is based on comparison of dose profiles generated by TPS and a Monte Carlo model for different beam energies, applicator sizes, and percentages of field blocking. Dose differences of up to 14% are observed at the depth of maximum dose. These discrepancies, often ignored in clinical evaluations, are attributable to inadequate modeling of scatter from applicators and blocks by TPS.

