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Related Experiment Video

Updated: Jun 10, 2026

Glucose-Stimulated Insulin Secretion via Perfusion through the Mice Vasculature with an Intact Pancreas

Glucose-Stimulated Insulin Secretion via Perfusion through the Mice Vasculature with an Intact Pancreas

Published on: July 25, 2025

[Insulinoma associated with pregnancy].

A Akca¹, K Mann, A Starke

¹Chirurgische Klinik I, Lukaskrankenhaus Neuss. AAkca@lukasneuss.de

Deutsche Medizinische Wochenschrift (1946)

|July 22, 2010

Summary

A rare insulinoma caused severe hypoglycemia in a postpartum woman. Surgical removal of the pancreatic tumor resolved symptoms, highlighting insulinoma as a critical diagnosis during pregnancy.

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Robotic Enucleation of an Intra-Pancreatic Insulinoma in the Pancreatic Head

Robotic Enucleation of an Intra-Pancreatic Insulinoma in the Pancreatic Head

Published on: January 3, 2020

Area of Science:

Endocrinology
Oncology
Gastroenterology

Background:

Postpartum hypoglycemia can be life-threatening, necessitating prompt diagnosis and management.
Insulinoma, a rare pancreatic neuroendocrine tumor, is a significant cause of endogenous hyperinsulinemic hypoglycemia.

Observation:

A 42-year-old woman presented with seizures and unconsciousness due to severe hypoglycemia (25 mg/dl) three weeks postpartum.
Diagnostic workup revealed hyperinsulinemic hypoglycemia consistent with Whipple's triad, despite negative imaging (CT, MRI, DOTATOC-PET).
Endoscopic ultrasound identified a 13 mm pancreatic tail mass.

Findings:

Laparoscopic enucleation successfully removed the insulinoma.
Postoperative blood glucose levels normalized, and the patient recovered fully.
Histological examination confirmed a pancreatic insulinoma.

Implications:

This case underscores the importance of considering insulinoma in the differential diagnosis of pregnancy-associated hypoglycemia.
Early and accurate diagnosis, aided by endoscopic ultrasound, is crucial for effective management.
Prompt surgical intervention leads to favorable outcomes for both mother and child.