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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

Comparison between maximal left ventricular wall thickness and left ventricular mass in patients with hypertrophic

Mateusz Spiewak1, Lidia Chojnowska, Lukasz A Małek

  • 1Department of Coronary Artery Disease and Structural Heart Diseases, Institute of Cardiology, Warsaw, Poland. mspiewak@ikard.pl

Kardiologia Polska
|July 22, 2010
PubMed

Insights

Maximal left ventricular wall thickness (MLVWT) does not accurately reflect left ventricular mass (LVM) in hypertrophic cardiomyopathy (HCM). Patients with similar MLVWT can have significantly different LVM, highlighting the need for comprehensive assessment in HCM.

Area of Science:

  • Cardiology
  • Medical Imaging

Background:

  • Cardiovascular magnetic resonance (CMR) provides accurate assessment of left ventricular (LV) dimensions and function.
  • Left ventricular mass (LVM) and maximal LV wall thickness (MLVWT) are prognostically significant in hypertrophic cardiomyopathy (HCM).

Purpose of the Study:

  • To compare MLVWT and LVM in patients with HCM.
  • To evaluate the relationship between MLVWT and LVM in HCM patients.

Main Methods:

  • Cardiac magnetic resonance (CMR) was used to measure MLVWT and LVM in 33 HCM patients.
  • MLVWT was determined from short-axis slices, and LVM was indexed to body surface area.
  • Exclusion criteria included prior alcohol septal ablation or surgical myectomy.

Main Results:

  • Mean LVM was 107.4 ± 30.9 g/m², higher in males than females (p=0.01).
  • Mean MLVWT was 23.4 ± 4.8 mm, with no significant difference between sexes (p=0.09).
  • No significant correlation was found between LVM and MLVWT (r=0.24, p=0.17), with substantial variability in LVM for similar MLVWT.

Conclusions:

  • MLVWT is not a reliable indicator of the degree of LV hypertrophy in HCM.
  • Significant differences in LVM exist among HCM patients with similar MLVWT.
  • A notable proportion of HCM patients exhibit normal or mildly increased LVM despite significant MLVWT.
Abstract

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