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Evaluation of renal function in children undergoing extracorporeal shock wave lithotripsy

A Fayad1, M G El-Sheikh, M Abdelmohsen

  • 1Urology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.

The Journal of Urology
|July 24, 2010
PubMed

Insights

Extracorporeal shock wave lithotripsy (ESWL) is safe for children, showing no signs of kidney scarring or reduced kidney function up to six months post-treatment. This study confirms ESWL

Area of Science:

  • Pediatric Urology
  • Nephrology
  • Medical Imaging

Background:

  • Pediatric kidney stone treatment requires careful consideration of potential long-term effects on growing organs.
  • Extracorporeal shock wave lithotripsy (ESWL) is a common modality, but its impact on pediatric renal development remains a concern.

Purpose of the Study:

  • To evaluate the safety of ESWL in children by assessing its effects on renal parenchymal scarring and glomerular filtration rate (GFR).

Main Methods:

  • A prospective study of 100 children (under 16) with renal stones treated with ESWL.
  • Renal parenchymal scarring was assessed using dimercapto-succinic acid (DMSA) scans, and GFR was measured using diethylenetriamine pentaacetic acid (DTPA) scans before and 6 months after ESWL.
  • Exclusion criteria included pre-existing renal scarring or vesicoureteral reflux.

Main Results:

  • No statistically significant renal parenchymal scarring was observed on DMSA scans post-ESWL.
  • No significant changes in GFR were detected on DTPA scans up to 6 months after treatment.
  • All 138 treated stones were evaluated for outcomes.

Conclusions:

  • ESWL is a safe and effective treatment for renal calculous disease in children up to 16 years old.
  • The procedure does not appear to negatively impact kidney function or cause scarring in the pediatric population.
  • ESWL offers a reliable option for pediatric kidney stone management without compromising renal health.
Abstract

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