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Updated: Jun 10, 2026

A Catheter-Related Candida albicans Infection Model in Mouse
Published on: March 22, 2024
[Bilateral emphysematous pyelonephritis caused by Candida glabrata: An exceptional entity]
Hajer Harrabi1, Chakib Marrakchi, Emna Daoud
1Service de maladies infectieuses, CHU Hédi Chaker, route El Aïn Km 0,5, 3029 Sfax, Tunisie.
Abstract:
Acute emphysematous pyelonephritis (AEP) is a severe form of urinary tract infection. It occurs usually in diabetics. The most concerned agents are the Gram-negative bacilli. We report a first case of bilateral AEP due to Candida glabrata, occurred in a 64-year-old diabetic woman. The clinical presentation started with fever and abdominal pains, without signs of urinary tract infection. Within six hours, the patient had developed a septic shock with renal failure and ketoacidosis. The diagnosis was confirmed by CT scan and the pathogen was isolated in urine. Despite antibiotic and antifungal treatment, she died from a septic shock. Acute emphysematous pyelonephritis due to Candida species is rare. However, the addition of antifungal therapy seems justified if a severe emphysematous pyelonephritis is associated with risk factors of Candida infection.
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