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Related Experiment Video

Updated: Jun 10, 2026

A Simplified Technique for In situ Excision of Cornea and Evisceration of Retinal Tissue from Human Ocular Globe

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Published on: June 12, 2012

The relationship between the cornea and the optic disc.

J M Kim¹, K H Park, S H Kim

¹Department of Ophthalmology, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul, Korea.

Eye (London, England)

|July 24, 2010

Summary

Large cup-to-disc ratios in the optic nerve are associated with larger, flatter corneas. This suggests a potential structural link between corneal properties and optic disc anatomy in healthy eyes.

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Area of Science:

Ophthalmology
Optometry
Anatomy

Background:

The anatomical relationship between the cornea and optic disc is not fully understood.
Investigating structural correlations can improve diagnostic accuracy in eye conditions.

Purpose of the Study:

To evaluate the structural relationship between the cornea and the optic disc in normal subjects.
To determine if corneal parameters correlate with optic disc measurements.

Main Methods:

Observational study of 205 healthy individuals.
Utilized optical coherence tomography, ultrasound pachymetry, and IOL master for measurements.
Corneal curvature, central corneal thickness, and white-to-white diameter were assessed.

Main Results:

Cup-to-disc ratio negatively correlated with corneal curvature and central corneal thickness.
Cup-to-disc ratio positively correlated with white-to-white diameter.
These associations remained significant in multiple regression analyses.

Conclusions:

Eyes with larger optic discs (higher cup-to-disc ratio) tend to have larger and flatter corneas.
A structural relationship between corneal morphology and optic disc size is suggested.
Findings may aid in analyzing the anatomical interplay between the cornea and optic disc.