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Abstract:
Cyclic AMP mediates the effects of many hormones on their target cells. Some of the mechanisms by which this occurs are discussed in this review. The role of cyclic AMP in regulating glycogen metabolism in liver and skeletal muscle is firmly established. Data suggesting that cyclic AMP mediates hormonally stimulated salivary gland amylase secretion, cardiac muscle contractility, smooth muscle relaxation, and platelet aggregation are summarized.