Related Experiment Videos
[Perforation risk and patient age. Risk analysis in acute sigmoid diverticulitis]
C Holmer1, K S Lehmann, J Gröne
1Klinik für Allgemein-, Gefäß- und Thoraxchirurgie, Chirurgische Klinik I, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, Berlin, Germany. christoph.holmer@charite.de
Insights
Younger patients (≤40) with acute sigmoid diverticulitis (SD) have more first episodes but no increased perforation risk. Treatment decisions for SD should prioritize inflammation severity over patient age.
Area of Science:
- Gastroenterology
- Surgical Gastroenterology
- Clinical Epidemiology
Context:
- Acute sigmoid diverticulitis (SD) is a common condition.
- Younger patients are often presumed to have a higher risk of perforation, necessitating early surgical intervention.
- This study investigates the relationship between patient age and the severity and outcomes of acute SD.
Purpose:
- To correlate the severity of sigmoid diverticulitis with patient age.
- To evaluate the risk of perforation in younger patients with acute SD.
- To inform surgical indications for acute SD in different age groups.
Summary:
- A cohort study of 959 patients with acute SD compared those ≤40 years (GI) to those >40 years (GII).
- First episodes of SD were more prevalent in GI (74.4%) than GII (46.3%).
- Perforation risk (Hansen and Stock IIb/IIc) and treatment modalities (emergency surgery, elective surgery, conservative treatment) did not significantly differ between the age groups.
Impact:
- Findings suggest that age alone is not a reliable predictor of perforation risk in acute SD.
- Treatment decisions for acute SD should be individualized based on inflammatory severity and patient-specific factors, not solely on age.
- This research may influence clinical guidelines regarding the management of acute sigmoid diverticulitis in younger populations.
Introduction:
It is often postulated that younger patients with acute sigmoid diverticulitis (SD) have an increased risk of perforation which constitutes an indication for early surgery. The aim of this study was to correlate the severity of sigmoid diverticulitis with patient age in order to check the surgical indication in younger patients.
Patients And Methods:
Patients with acute SD from January 1998 to June 2009 were included. Two age groups were distinguished: group I (GI) ≤40 years in age and group II (GII) >40 years. The perforation risk associated with first episode SD was determined by multivariate analysis. SD was classified according to Hansen and Stock (H/S).
Results:
In the total cohort of 959 patients, including 86 in GI (8.9%) and 873 in GII (91.1%) 468 had a first episode, with 64 in GI (13.7%) and 404 in GII (86.3%). The proportion of first episodes was 74.4% in GI and 46.3% in GII (p<0.001). The perforation risk did not differ (H/S IIb: 29.7% in GI vs. 29.2% in GII, p=0.938; H/S IIc: 25% in GI vs. 25% in GII, p=1). Treatment regimes were (GI vs. GII) emergency operations 25% vs. 25% (p=1), elective operations 17.2% vs. 10% (p=0.096) and conservative treatment 57.8% vs. 64.9% (p=0.276).
Conclusion:
First episodes of SD were more frequent in younger patients (≤40) and did not involve a higher risk of perforation. The indication for treatment of acute SD should not be based on age but on the severity of inflammation and the individual situation of patients.
Related Concept Videos
Diverticular Disease of the Colon
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Appendicitis
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...