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Process Optimization using High Throughput Automated Micro-Bioreactors in Chinese Hamster Ovary Cell Cultivation
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Model-based analysis and optimization of bioreactor for hematopoietic stem cell cultivation

M T A P Kresnowati1, G M Forde, X D Chen

  • 1Bioprocess and Microbiology Laboratory, Department of Chemical Engineering, Faculty of Industrial Technology, Bandung Institute of Technology, Ganesha 10, Bandung 40132, Indonesia. kresnowati@che.itb.ac.id

Bioprocess and Biosystems Engineering
|July 24, 2010
PubMed
Summary

Limited hematopoietic stem cell (HSC) availability is a challenge. This study developed a mathematical model and feeding strategies for ex vivo HSC cultivation in a microchannel bioreactor, improving cell yield.

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