Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Application of Integration: Problem Solving01:30

Application of Integration: Problem Solving

The process of breathing involves the periodic intake and expulsion of air, known as the respiratory cycle, which typically lasts about five seconds. Modeling the volume of air inhaled into the lungs as a function of time provides insight into both the dynamics and efficiency of pulmonary ventilation. This volume is determined by integrating the airflow rate over time, which captures the cumulative effect of air entering the lungs.Sinusoidal Model of AirflowAirflow during respiration is not...
Mechanism of Breathing I: Inspiration01:30

Mechanism of Breathing I: Inspiration

Introduction to Inspiration: The Respiratory System in Action
The respiratory system, an essential network for breathing, comprises the conducting and respiratory zones, each playing a crucial role in the overall process of respiration. Let us explore the detailed mechanism of inspiration, or inhalation, which is the first phase of the respiratory cycle.
Pathway of Air during Inspiration
During inspiration, air enters our body through the nose or mouth and moves through the conducting zone,...
Physiological Control of Respiration01:23

Physiological Control of Respiration

Introduction
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
Pulmonary Ventilation: Inhalation01:24

Pulmonary Ventilation: Inhalation

Pulmonary ventilation is a vital process that ensures the exchange of oxygen and carbon dioxide in the lungs. It refers to the movement of air into and out of the lungs, enabling the body to obtain oxygen and remove waste carbon dioxide. In this article, we will explore the intricacies of pulmonary ventilation, including its underlying principles, mechanisms, and the interplay of pressures within the respiratory system.
Boyle's law becomes particularly pertinent when examining respiratory...
Breathing01:05

Breathing

The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ultrasound-assisted valorization of Posidonia oceanica polysaccharides: Discovery of novel monosaccharides and enhanced multifunctional bioactivity.

International journal of biological macromolecules·2026
Same author

Non-invasive left ventricular contractility indices derived from thoracocardiography in rats.

Scientific reports·2026
Same author

Polyphenolic Profile, Antioxidant, Antibacterial and Antidiabetic Activities of Acorns from Three Tunisian <i>Quercus</i> L. Species.

Plants (Basel, Switzerland)·2026
Same author

Continuous non-invasive extraction of hemodynamic variables from thoracocardiographic signals using the ensemble averaging technique: validation in anesthetized rats without ventilatory support.

Physiological measurement·2025
Same author

Integrating movement analysis and cardiorespiratory assessment in smart electrically assisted bicycle sessions- Proof of concept.

Medical engineering & physics·2025
Same author

Inspiratory and expiratory sinus arrhythmia in healthy human.

Physiological reports·2025

Related Experiment Video

Updated: Jun 10, 2026

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways
09:39

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

Published on: May 9, 2016

A simple dynamic model of respiratory pump.

Pascale Calabrese1, Pierre Baconnier, Aicha Laouani

  • 1Laboratoire TIMC-IMAG, UMR 5525, Pavillon Taillefer Faculté de médecine de Grenoble , Université Joseph Fourier-Grenoble 1, CNRS, 38700 La Tronche, France. Pascale.Calabrese@imag.fr

Acta Biotheoretica
|July 24, 2010
PubMed
Summary

This study presents a simple model of chest wall mechanics, simulating respiratory muscle forces and passive elastic properties. The model accurately predicts airflow in healthy individuals, aiding understanding of breathing mechanics.

More Related Videos

Design and Implementation of a Rat Ex Vivo Lung Perfusion Model
04:38

Design and Implementation of a Rat Ex Vivo Lung Perfusion Model

Published on: May 26, 2023

Phase-Resolved Functional Lung MRI for Pulmonary Ventilation and Perfusion (V/Q) Assessment
05:56

Phase-Resolved Functional Lung MRI for Pulmonary Ventilation and Perfusion (V/Q) Assessment

Published on: August 9, 2024

Related Experiment Videos

Last Updated: Jun 10, 2026

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways
09:39

A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways

Published on: May 9, 2016

Design and Implementation of a Rat Ex Vivo Lung Perfusion Model
04:38

Design and Implementation of a Rat Ex Vivo Lung Perfusion Model

Published on: May 26, 2023

Phase-Resolved Functional Lung MRI for Pulmonary Ventilation and Perfusion (V/Q) Assessment
05:56

Phase-Resolved Functional Lung MRI for Pulmonary Ventilation and Perfusion (V/Q) Assessment

Published on: August 9, 2024

Area of Science:

  • Physiology
  • Biomechanics
  • Respiratory System Modeling

Background:

  • Chest wall motion is driven by complex force interactions.
  • Previous models exist, but incorporating dynamic respiratory properties is crucial.

Purpose of the Study:

  • To develop and validate a simple model of chest wall mechanics.
  • To analyze the interaction of forces governing chest wall motion.
  • To assess the model's ability to represent rib cage and abdominal movement during breathing.

Main Methods:

  • A model based on Hillman and Finucane's lever system was adapted.
  • Passive elements (rib cage, abdomen) modeled as elastic compartments.
  • Active respiratory muscle forces applied to both compartments.
  • Model parameters identified using experimental data (airflow, rib cage, and abdomen motion) from 11 healthy volunteers under various loading conditions.

Main Results:

  • The model successfully simulated airflow, with a determination coefficient (R²) ≥ 0.70 in several breaths across individuals and conditions.
  • The model demonstrated good agreement with measured airflow signals.
  • The model effectively captures the dynamic behavior of the chest wall.

Conclusions:

  • This simplified model provides a useful representation of chest wall mechanics.
  • The model can aid in interpreting the relative motion of the rib cage and abdomen during quiet breathing.
  • Further research can explore its application in different respiratory states.