Brugada like pattern in ECG with drug overdose
H S Kiran1, Y S Ravikumar, M R Jayasheelan
1JSS Medical College & Hospital, Mysore.
The Journal of the Association of Physicians of India
|July 27, 2010
Summary
Tricyclic antidepressant overdose can cause dangerous heart problems. This case shows a Brugada-like pattern on ECG in Dothiepin overdose, highlighting ECG
Area of Science:
- Cardiology
- Clinical Toxicology
- Pharmacology
Background:
- Tricyclic antidepressants (TCAs) are associated with significant cardiotoxicity in overdose scenarios.
- Electrocardiography (ECG) plays a crucial role in identifying TCA exposure and predicting patient outcomes.
- Various ECG abnormalities can manifest following TCA overdose.
Observation:
- A case of Dothiepin overdose was analyzed.
- The patient presented with a Brugada-like electrocardiographic pattern.
- The ECG findings included a right bundle branch block (RBBB).
Findings:
- The Brugada-like pattern and RBBB observed in this Dothiepin overdose case resolved spontaneously.
- This highlights the dynamic nature of ECG changes in TCA toxicity.
Implications:
- ECG monitoring is essential for managing patients with suspected tricyclic antidepressant overdose.
- Recognizing specific ECG patterns, such as Brugada-like changes, can aid in diagnosis and prognosis.
- This case underscores the importance of prompt cardiac assessment in TCA toxicity.
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