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[Prevalence of celiac disease in children with chronic diarrhea in China]

Xin-qiong Wang1, Wei Liu, Jun-jie Xu

  • 1Department of Pediatrics, Shanghai Ruijin Hospital Affiliated to School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China.

Zhonghua Er Ke Za Zhi = Chinese Journal of Pediatrics
|July 27, 2010
PubMed

Insights

Celiac disease (CD) affects children with chronic diarrhea in China, with 12% suspected and one confirmed case. Early diagnosis and gluten-free diets are crucial for managing pediatric CD.

Area of Science:

  • Gastroenterology
  • Pediatrics
  • Immunology

Context:

  • Chronic diarrhea is a common pediatric condition in China.
  • Celiac disease (CD) prevalence in this population was previously unknown.
  • Limited awareness of CD among Chinese pediatricians may delay diagnosis.

Purpose:

  • To determine the prevalence of celiac disease in Chinese children presenting with chronic diarrhea.
  • To highlight the importance of considering CD in the differential diagnosis of pediatric chronic diarrhea.

Summary:

  • A study of 118 hospitalized children with chronic diarrhea in China found 12% (14/118) were suspected of having celiac disease, with one confirmed case.
  • Confirmed celiac disease patients showed malnutrition, anemia, and villous atrophy on biopsy.
  • Gluten-free diet (GFD) treatment proved effective for the confirmed case.

Impact:

  • This study provides the first evidence of celiac disease in Chinese children with chronic diarrhea.
  • It underscores the need for increased awareness and diagnostic vigilance for CD among Chinese pediatricians.
  • Findings may influence diagnostic guidelines and improve patient outcomes for pediatric CD in China.
Abstract

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