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Updated: Jun 10, 2026

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
[Interventional catheterization management for patients with postoperative residual cardiovascular malformations]
Zhi-wei Zhang1, Yu-mei Xie, Shu-shui Wang
1Department of Pediatric Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Science, Guangzhou 510100, China.
Interventional therapy effectively treats complex congenital heart defects with residual lesions. Procedures like angioplasty and stenting improved patient outcomes and reduced pressure gradients safely.
Area of Science:
- Cardiology
- Interventional Cardiology
- Pediatric Cardiology
Background:
- Complex congenital heart defects often present with unrepaired or residual lesions post-surgery.
- These residual issues can lead to significant morbidity and impact patient quality of life.
Purpose of the Study:
- To assess the effectiveness and safety of interventional therapy for complex congenital heart defects.
- To evaluate outcomes in patients with unrepaired or postoperative residual lesions.
Main Methods:
- A cohort of 42 patients (mean age 6 years) underwent interventional procedures between 1998 and 2009.
- Interventions included occlusion of major aorto-pulmonary collateral arteries (MAPCAs), device closure of septal defects, and balloon angioplasty/stenting for stenosis.
Main Results:
- Successful occlusion of 23 MAPCAs in 17 patients.
- Successful device closure in 15 patients with minimal residual shunting in one.
- Significant improvement in exercise capacity and decreased pressure gradients post-angioplasty/stenting, with no major complications or arrhythmias.
Conclusions:
- Interventional therapy offers a safe and effective treatment option for complex congenital heart defects.
- It successfully addresses unrepaired or postoperative residual lesions, improving patient hemodynamics and functional status.
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