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Updated: Jun 10, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
[Pathological characteristics and clinical significance of macrochilia secondary to venular malformation]
Wei Wang1, Xiao-xi Lin, Gang Ma
1Department of Plastic and Reconstructive Surgery, Ninth People's Hospital, Shanghai Jiao Tong University, Shanghai 200011, China.
Objective:
To analyze the histologic characteristics of macrochilia secondary to port-wine stain and to elucidate the possible mechanism.
Methods:
Twenty-one cases of macrochilia secondary to venular malformation were included and the histology of the lesions was observed by light microscope.
Results:
Histological examination revealed vascular abnormalities and a number of widely distributed hamartomatous changes in macrochilia secondary to venular malformation. The average vessel diameter is (39.8 +/- 15.7) microm. The degree of hamartomatous change: mild (1 case), moderate (7 cases) and severe (13 cases).
Conclusions:
The complex hamartomatous changes suggest a genetically determined, multilineage developmental field defect in the pathogenesis of venular malformation.
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