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Related Concept Videos

The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...

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Related Experiment Video

Updated: Jun 10, 2026

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma
10:58

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

Published on: February 22, 2015

[Neonatal tumors].

Carla Costa1, Gustavo Rocha, Marta Grilo

  • 1Serviço de Neonatologia, Hospital de São João, Porto.

Acta Medica Portuguesa
|July 27, 2010
PubMed
Summary
This summary is machine-generated.

Neonatal tumors present unique challenges, with teratomas and lymphangiomas being common. Prenatal diagnosis aids in planning multidisciplinary care for improved outcomes in these rare pediatric neoplasms.

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Neonatal Subventricular Zone Electroporation
08:06

Neonatal Subventricular Zone Electroporation

Published on: February 11, 2013

Related Experiment Videos

Last Updated: Jun 10, 2026

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma
10:58

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

Published on: February 22, 2015

Neonatal Subventricular Zone Electroporation
08:06

Neonatal Subventricular Zone Electroporation

Published on: February 11, 2013

Area of Science:

  • Pediatric Oncology
  • Neonatal Medicine
  • Tumor Biology

Context:

  • Neonatal tumors are rare and distinct from adult/older pediatric cancers.
  • Diagnosis and treatment pose unique challenges in newborns.
  • This study reviews clinical data from a single institution over a decade.

Purpose:

  • To evaluate the clinical aspects of neonatal tumors.
  • To analyze the types, diagnoses, and outcomes of tumors in newborns.
  • To highlight the importance of prenatal diagnosis and multidisciplinary care.

Summary:

  • Retrospective analysis of 32 neonatal tumor cases (1996-2006).
  • Common tumors included teratoma (n=8), lymphangioma (n=7), and neuroblastoma (n=6).
  • Prenatal diagnosis in 50% of cases facilitated multidisciplinary planning; most patients had good outcomes, except for one case of acute lymphoblastic leukemia.

Impact:

  • Prenatal diagnosis enables proactive, multidisciplinary management strategies.
  • International collaboration is essential for advancing knowledge and improving prognosis for rare neonatal tumors.
  • Findings underscore the need for specialized care pathways for pediatric neoplasms.