A "primary" thrombotic syndrome: absence of anti-phospholipid antibodies

A patient presenting fetal loss, livedo reticularis, severe migraine crises, myocardial infarction and thrombotic vasculopathy of both external iliac arteries is described. The serologic study showed absence of antiphospholipid antibodies (aPL), suggesting that in some cases the presence of these antibodies may be a consequence of tissue damage.