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Updated: Jun 10, 2026

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Palinopsia.

Brian Abert¹, Pauline F Ilsen

¹Vista Eye Care, Thornton, Colorado 80602, USA. brian.abert@gmail.com

Optometry (St. Louis, Mo.)

|July 27, 2010

Summary

Palinopsia, a visual disturbance, can stem from various causes including drug use, head trauma, and prescribed medications. Recognizing its distinct symptoms is crucial for accurate diagnosis and identifying underlying conditions.

Area of Science:

Ophthalmology
Neurology
Psychiatry

Background:

Palinopsia is a distinct visual disturbance with diverse associations, including neurological and psychiatric conditions.
While resembling other visual phenomena, palinopsia's unique characteristics warrant specific diagnostic consideration.
Diagnostic approaches include patient history, visual field testing, and neuroimaging.

Observation:

Four distinct cases of palinopsia are presented, illustrating varied etiologies.
Case 1: Palinopsia associated with extensive lysergic acid diethylamide (LSD) use.
Case 2: Palinopsia secondary to head trauma from a motor vehicle accident.
Case 3: Palinopsia onset after trazodone prescription for insomnia.
Case 4: Multiple potential etiologies identified.

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Findings:

Palinopsia can be triggered by recreational drug use (LSD), traumatic brain injury, and certain pharmaceuticals (trazodone).
The presented cases highlight the broad spectrum of potential causes for palinopsia.
Accurate identification of palinopsia's cause is essential for appropriate management.

Implications:

Optometrists and clinicians must be aware of palinopsia symptoms to avoid misdiagnosis.
Understanding palinopsia's pathophysiology aids in identifying underlying systemic dysfunctions.
Recognizing palinopsia can alleviate patient distress and guide necessary medical treatment.