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Updated: Jun 10, 2026

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors
Published on: September 10, 2013
8-Hydroxyquinoline dansylates modified with PAMAM dendrimer as fluorescent Fe+ sensors
Qi Zhang1, Yaowu Sha, Jin-Hui Wang
1Department of Chemistry, The Key Laboratory of Bioorganic Phosphorous Chemistry and Chemical Biology, Tsinghua University, Beijing 100084, China.
Abstract:
A series of fluorescent sensors based on 8-hydroxyquinoline dansylate as core and dendritic PAMAM as shell were synthesized. Their fluorescence characteristic and fluorescent sensing behavior toward metal ions were studied in water/methanol (1: 1, v/v). The sensors exhibit good selectivity and sensitivity for Fe(3+) ion and to some extent for Cr(3+) ion. The third generation dendrimer has the better sensitivity than the first and second generations.

