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Updated: Jun 10, 2026

Monitoring the Mechanical Evolution of Tissue During Neural Tube Closure of Chick Embryo
Published on: November 10, 2023
[Neural-Tube Defects mortality in children under 5 years of age in Mexico, 1998 to 2006]
Javier Valdés-Hernández1, Sonia Canún-Serrano, Aldelmo E Reyes-Pablo
1Dirección General de Epidemiología, Secretaría de Salud, Delegación Alvaro Obregón, México DF, México. javiervahe@yahoo.com.mx
Objectives:
To analyze mortality due to neural-tube defects (NTD) in children under 5 years of age, 1998-2006 and select priority municipalities and compare them to those selected for birth defects (BD).
Materials And Methods:
Sources of data were the Secretary of Health and the National Institute of Statistics and Geography. Spatial analysis was used to select municipalities and criteria were based on percentiles.
Results:
Deaths due to NTD represented 39.63% - 56.91% of nervous system defects and decreased 53%; the rate decreased 59%. Regarding deaths, 86-93% occurred in children under 5 years of age. The rate for children under 1 year of age decreased 51%, and 60% for 1-4 years of age. A total of 205 municipalities resulted in being high priority, where 63.23% of deaths were concentrated. The Kappa index between BD/NTD priority municipalities was 0.75.
Conclusion:
Actions against NTD should be emphasized in the selected municipalities.
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