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Alzheimer Disease l: Introduction01:29

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Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Alzheimer disease involves structural changes in the brain that begin long before symptoms appear. The most distinctive features are extracellular neuritic plaques and intracellular neurofibrillary tangles.Neuritic plaques form in the cerebral cortex and around blood vessels. These plaques contain a dense core of beta-amyloid (Aβ)—a toxic protein fragment that clumps outside neurons. The core is surrounded by damaged neuronal extensions, as well as reactive astrocytes and microglia. Abnormal...
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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Pathways to problem gambling in seniors.

Luxana Connie Tirachaimongkol1, Alun Conrad Jackson, Jane Elizabeth Tomnay

  • 1Problem Gambling Research and Treatment Centre, The University of Melbourne, Parkville, Australia. ctir@unimelb.edu.au

Journal of Gerontological Social Work
|July 27, 2010
PubMed
Summary

Problem gambling in older adults, especially those with late-onset issues, is understudied. This research identifies key risk and protective factors to aid interventions for seniors facing gambling problems.

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Area of Science:

  • Gerontology
  • Psychology
  • Public Health

Background:

  • Problem gambling in older adults is an emerging concern.
  • Late-onset gambling problems require specific understanding.
  • Existing models need adaptation for senior populations.

Purpose of the Study:

  • To propose pathways to problem gambling in individuals aged 55 and above.
  • To focus on late-onset gambling problems rather than lifetime prevalence.
  • To inform interventions for vulnerable older adults experiencing gambling issues.

Main Methods:

  • Literature review of senior-specific gambling research.
  • Extraction of gambling-related risk and protective factors.
  • Thematic analysis and classification of identified factors.

Main Results:

  • Identified three main clusters of factors: individual vulnerability, social/environmental influences, and behavioral regulation.
  • Factors were categorized based on their relevance to late-life problem gambling.
  • Established a framework for understanding gambling problems in older adults.

Conclusions:

  • Understanding the unique pathways to problem gambling in older adults is crucial.
  • The identified factors provide a basis for targeted interventions.
  • Further research can refine these pathways for effective support strategies.