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Updated: Jun 10, 2026

Barnes Maze Testing Strategies with Small and Large Rodent Models
Published on: February 26, 2014
Sex differences in the strategies used by rats to solve a navigation task
Clara A Rodríguez1, Angélica Torres, N J Mackintosh
1Departament de Psicologia Basica, Passeig de la Vall d'Hebron 171, 08035-Barcelona, Spain.
Abstract:
Rats were trained in a triangular-shaped pool to find a hidden platform, whose location was defined in terms of two sources of information, a landmark outside the pool and a particular corner of the pool. Subsequent test trials without the platform pitted these two sources of information against one another. This test revealed a clear sex difference. Females spent more time in an area of the pool that corresponded to the landmark, whereas males spent more time in the distinctive corner of the pool even though further tests revealed that both sexes had learned about the two sources of information by presenting cues individually. The results agree with the claim that males and females use different types of information in spatial navigation.

