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[Cardiorenal interrelationships in elderly patients with arterial hypertension]

L T Pimenov, N F Odintsova

    Kardiologiia
    |July 28, 2010
    PubMed

    Insights

    Elderly patients with arterial hypertension (AH) exhibit more significant blood pressure fluctuations and morning surges. They also show higher rates of kidney and cardiovascular issues compared to younger individuals.

    Area of Science:

    • Cardiology
    • Nephrology
    • Gerontology

    Background:

    • Arterial hypertension (AH) is a prevalent condition affecting cardiovascular and renal health.
    • Aging is associated with physiological changes that can exacerbate hypertension-related complications.

    Purpose of the Study:

    • To compare the clinical and functional characteristics of the kidney and cardiovascular system in elderly patients with AH.
    • To contrast these findings with data from younger and middle-aged patients diagnosed with AH.

    Main Methods:

    • The study included 142 patients with arterial hypertension.
    • Echocardiography, 24-hour blood pressure monitoring, and renal function tests were performed.
    • Patients were categorized into elderly (≥60 years) and younger (≤59 years) groups.

    Main Results:

    • Elderly patients with AH demonstrated increased blood pressure variability and morning elevation.
    • Diastolic dysfunction and endothelial dysfunction were more prevalent in the elderly group.
    • Microalbuminuria and reduced glomerular filtration rate were significantly more frequent in elderly hypertensive patients.

    Conclusions:

    • Aging significantly impacts the cardiovascular and renal systems in patients with arterial hypertension.
    • Elderly hypertensive patients present with distinct pathophysiological characteristics requiring tailored management strategies.
    • Further research is warranted to explore age-specific therapeutic interventions for hypertension.
    Abstract

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