Related Experiment Video
Updated: Jun 10, 2026

Reactivation of Demembranated Cell Models in Chlamydomonas reinhardtii
Published on: May 6, 2022
Select acetophenones modulate flagellar motility in chlamydomonas
Shakila K Evans1, Austin A Pearce, Prudence K Ibezim
1Department of Biological Sciences, Sam Houston State University, Huntsville, TX 77341, USA.
Abstract:
Acetophenones were screened for activity against positive phototaxis of Chlamydomonas cells, a process that requires co-ordinated flagellar motility. The structure-activity relationships of a series of acetophenones are reported, including acetophenones that affect flagellar motility and cell viability. Notably, 4-methoxyacetophenone, 3,4-dimethoxyacetophenone, and 4-hydroxyacetophenone induced negative phototaxis in Chlamydomonas, suggesting interference with activity of flagellar proteins and control of flagellar dominance.
Related Concept Videos
Channel Rhodopsins
Rhodopsins belong to the family of cell surface proteins called G-protein coupled receptors,...
Chemotaxis in E. coli
Flagella and Motility in Bacteria
Direct-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship
The direct-acting...
Diversity of Protists II
Indirect-Acting Cholinergic Agonists: Mechanism of Action
Reversible inhibitors like edrophonium bind to a specific part of the enzyme called the anionic catalytic site. They form noncovalent bonds, which means they are not strongly attached to the enzyme. This creates a temporary and less stable enzyme–inhibitor complex, leading to...

