Weight estimation in paediatrics: a comparison of the APLS formula and the formula 'Weight=3(age)+7'

Mark D Luscombe1, Ben D Owens, Derek Burke

  • 1Anaesthetic Department, Doncaster Royal Infirmary, Doncaster, UK. mark.luscombe@dbh.nhs.uk

Insights

The formula Weight=2(age+4) significantly underestimates pediatric weight, potentially leading to under-resuscitation. A new formula, Weight=3(age)+7, offers a more accurate estimation for children aged 1-13 years.

Area of Science:

  • Pediatric emergency medicine
  • Clinical pharmacology
  • Biostatistics

Background:

  • Accurate weight estimation is critical for pediatric resuscitation.
  • Current weight estimation formulas may not reflect contemporary pediatric anthropometrics.

Purpose of the Study:

  • To evaluate the accuracy of the current pediatric weight estimation formula: Weight(kg)=2(age+4).
  • To assess a newly derived formula: Weight(kg)=3(age)+7.
  • To compare the validity of both formulas in a pediatric emergency department population.

Main Methods:

  • Retrospective study of 93,827 children aged 1-16 years.
  • Data collected from pediatric attendances at a major UK emergency department (ED).
  • Comparison of actual weights against estimated weights using both formulas.

Main Results:

  • The formula Weight=2(age+4) underestimated weights by a mean of 33.4%.
  • The formula Weight=3(age)+7 underestimated weights by a mean of 6.9%.
  • The formula Weight=3(age)+7 was applicable from 1 to 13 years.

Conclusions:

  • The current weight estimation formula leads to significant underestimation, risking under-resuscitation.
  • The formula Weight=3(age)+7 provides a safer and more accurate weight estimate for children aged 1 year to puberty.
  • Improved weight estimation is crucial for safe and effective pediatric emergency care.
Abstract

Related Concept Videos

Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration01:28

Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration

Glomerular filtration rate (GFR) can be estimated from serum creatinine using the modification of diet in renal disease (MDRD) formula or the chronic kidney disease–epidemiology collaboration (CKD–EPI) equation. Both methods are widely used in clinical practice to assess kidney function and guide treatment decisions.The MDRD equation does not require weight or height measurements and is normalized to the body surface area of 1.73 m², considered the average adult surface area. This equation is...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Experimental Determination of Chemical Formula02:37

Experimental Determination of Chemical Formula

The elemental makeup of a compound defines its chemical identity, and chemical formulas are the most concise way of representing this elemental makeup. When a compound’s formula is unknown, measuring the mass of its constituent elements is often the first step in determining the formula experimentally.