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A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
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In vitro selection of structure-switching, self-reporting aptamers

Seung Soo Oh1, Kory Plakos, Xinhui Lou

  • 1Materials Department, University of California, Santa Barbara, CA 93106, USA.

Proceedings of the National Academy of Sciences of the United States of America
|July 28, 2010
PubMed
Summary

Researchers developed self-reporting aptamers (SRAs) that signal target binding via fluorescence. This innovation simplifies detection without extra steps, offering a new tool for molecular diagnostics.

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