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Fever--an update
John H Becker1, Stephanie C Wu
1Basic Biomedical Sciences, Dr. William M. Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA. john.becker@rosalindfranklin.edu
Journal of the American Podiatric Medical Association
|July 28, 2010
Summary
Fever, a body temperature rise mediated by cytokines, is a common clinical sign. This review covers fever causes, management, and postoperative issues, particularly in podiatric surgery.
Area of Science:
- Physiology
- Immunology
- Clinical Medicine
Background:
- Fever is a non-specific bodily response to infection or injury, involving cytokine release and prostaglandin-mediated temperature increase.
- Physicians utilize fever as a diagnostic and prognostic tool, though fevers of unknown origin present challenges.
- Postoperative fevers can indicate stress/trauma (early) or serious complications like wound infection (later).
Purpose of the Study:
- To review the causes, types, clinical management, and postoperative consequences of fever.
- To highlight the significance of fever in diagnosis and prognosis.
- To discuss fever specifically within the context of podiatric medicine and surgery.
Main Methods:
- Literature review of fever causes, types, and management.
- Analysis of postoperative fever patterns and their implications.
- Examination of fever incidence in podiatric procedures.
Main Results:
- Fever is a complex physiological response with diverse triggers.
- Early postoperative fevers are often benign, while later fevers suggest significant pathology.
- Certain lower extremity surgical procedures are associated with a higher likelihood of fever.
Conclusions:
- Fever is a critical clinical indicator requiring careful evaluation.
- Understanding fever's origins is essential for effective patient management, especially post-surgery.
- Podiatric surgeons must be vigilant for fever as a potential complication.
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Types of Fever
Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
Here are the different types of fever:
Patterns of Fever
Before understanding the types and patterns of fever, it is essential to know its phases.
Increased Body Temperature
A body temperature above 38°C (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Methods of reducing fever
The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Pharmacological Methods of Reducing Fever:
Decreased Body Temperature
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Yellow Fever
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