Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Fever01:25

Types of Fever

Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
Patterns of Fever01:26

Patterns of Fever

Before understanding the types and patterns of fever, it is essential to know its phases.
Increased Body Temperature01:25

Increased Body Temperature

A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Decreased Body Temperature01:29

Decreased Body Temperature

A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...
Yellow Fever01:18

Yellow Fever

Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

American Limb Preservation Society, Diabetic Foot Conference, and More: How to Get Involved in Limb Preservation.

Clinics in podiatric medicine and surgery·2026
Same author

A tumor-associated photoreceptor signature unifies distinct central nervous system malignancies.

Cancer cell·2026
Same author

A Multi-Centre, Randomised, Controlled Clinical Trial Assessing Cryopreserved Ultra-Thick Human Amniotic Membrane in the Treatment of Complex Diabetic Foot Ulcers.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society·2025
Same author

Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target.

Cancer cell·2025
Same author

Arrested development: the dysfunctional life history of medulloblastoma.

Genes & development·2024
Same author

UHRF1 overexpression promotes osteosarcoma metastasis through altered exosome production and AMPK/SEMA3E suppression.

Oncogenesis·2022
Same journal

Offloading Adherence for Appearance's Sake?

Journal of the American Podiatric Medical Association·2026
Same journal

Effect of Insoles on Plantar Fascia Tension During Running in Individuals with Flatfoot.

Journal of the American Podiatric Medical Association·2026
Same journal

Reducing Lower Extremity Amputations via Peer Support Interventions: A Scoping Review.

Journal of the American Podiatric Medical Association·2026
Same journal

Quantitative Assessment of the Correlation Between 'COVID Toes' Search Volume and COVID-19 Case Incidence and Mortality Dynamics: A Longitudinal Data-Driven Approach.

Journal of the American Podiatric Medical Association·2026
Same journal

Reconsidering Nerve Decompression Surgery in Diabetes Foot Complications.

Journal of the American Podiatric Medical Association·2026
Same journal

Quantification of the Mechanical Response of the Plantar Fascia to Changes in Rearfoot Position.

Journal of the American Podiatric Medical Association·2026
See all related articles

Related Experiment Videos

Fever--an update.

John H Becker1, Stephanie C Wu

  • 1Basic Biomedical Sciences, Dr. William M. Scholl College of Podiatric Medicine at Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA. john.becker@rosalindfranklin.edu

Journal of the American Podiatric Medical Association
|July 28, 2010
PubMed
Summary
This summary is machine-generated.

Fever, a body temperature rise mediated by cytokines, is a common clinical sign. This review covers fever causes, management, and postoperative issues, particularly in podiatric surgery.

Related Experiment Videos

Area of Science:

  • Physiology
  • Immunology
  • Clinical Medicine

Background:

  • Fever is a non-specific bodily response to infection or injury, involving cytokine release and prostaglandin-mediated temperature increase.
  • Physicians utilize fever as a diagnostic and prognostic tool, though fevers of unknown origin present challenges.
  • Postoperative fevers can indicate stress/trauma (early) or serious complications like wound infection (later).

Purpose of the Study:

  • To review the causes, types, clinical management, and postoperative consequences of fever.
  • To highlight the significance of fever in diagnosis and prognosis.
  • To discuss fever specifically within the context of podiatric medicine and surgery.

Main Methods:

  • Literature review of fever causes, types, and management.
  • Analysis of postoperative fever patterns and their implications.
  • Examination of fever incidence in podiatric procedures.

Main Results:

  • Fever is a complex physiological response with diverse triggers.
  • Early postoperative fevers are often benign, while later fevers suggest significant pathology.
  • Certain lower extremity surgical procedures are associated with a higher likelihood of fever.

Conclusions:

  • Fever is a critical clinical indicator requiring careful evaluation.
  • Understanding fever's origins is essential for effective patient management, especially post-surgery.
  • Podiatric surgeons must be vigilant for fever as a potential complication.