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Subregional localization of the chromosome 21 loci D21S24 and D21S26 using physical mapping techniques
W Van Hul1, H Backhovens, G Van Camp
1Department of Biochemistry, Born-Bunge Foundation, University of Antwerp (UIA), Belgium.
Human Genetics
|June 1, 1991
Abstract:
We were able to refine the chromosomal position of two existing marker loci, using an extended chromosome 21 somatic cell hybrid panel. The locus D21S26 mapped in the region 21q11.2-q21.1, and the locus D21S24 in 21q22.1-q22.2. Physical and genetic analysis indicated that D21S26 is tightly linked to D21S13 and D21S16, two markers previously linked to familial Alzheimer's disease.