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A sterile male with 45,X0 and a Y;22 translocation
J Arnemann1, S Schnittger, G K Hinkel
1Institut für Humangenetik, Universität Göttingen, Federal Republic of Germany.
Human Genetics
|June 1, 1991
Abstract:
Cytogenetic analysis of a 20-year-old sterile male revealed a 45,X0 karyotype with no evidence for Y-chromosomal material on any of the chromosomes analysed by Q-, G- and C-banding. DNA analysis with 17 different Y chromosome-derived probes revealed the presence of Yp DNA sequences in the patient's genome. In situ hybridization with the Yp-derived probe pJA36B disclosed a translocation of Y-chromosomal material onto the short arm of a chromosome 22.