Related Experiment Video
Updated: Jun 10, 2026

Metagenomic Next-Generation Sequencing of Cerebrospinal Fluid for the Detection of Central Nervous System Pathogens
Published on: April 17, 2026
Clinical usefulness of cerebrospinal fluid evaluation
1Sten Fredrikson, Department of Clinical Neuroscience, Division of Neurology R54, Karolinska Institutet, Karolinska University Hospital Huddinge, S-141 86 Stockholm, Sweden, Tel: +46 736 841 179, Fax: +46 877 448 222,
Abstract:
The importance of analysis of cerebrospinal fluid (CSF), especially oligoclonal IgG bands, in the diagnosis of multiple sclerosis (MS) and its predictive value in patients with clinically isolated syndromes has recently been evaluated and confirmed in several studies. Despite the focus on magnetic imaging techniques in modern MS diagnostic criteria, evaluation of CSF is of great usefulness both as a diagnostic and predictive tool.
Related Concept Videos
Cerebrospinal Fluid
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain.
Viral Meningitis

