Related Experiment Video
Updated: Jun 10, 2026

Mouse Round Spermatid Injection
Published on: January 26, 2024
Contribution of male age to outcomes in assisted reproductive technologies
Brian W Whitcomb1, Renée Turzanski-Fortner, Kevin S Richter
1Division of Biostatistics and Epidemiology, University of Massachusetts School of Public Health and Health Sciences, Amherst, Massachusetts, USA.
Objective:
To evaluate the relationship between male age and pregnancy outcome in donor oocyte assisted reproductive technology cycles.
Design:
Retrospective cohort.
Setting:
Private IVF center.
Patient(S):
A total of 1,392 donor cycles from 1,083 female recipients and their male partners.
Intervention(S):
Oocyte donor cycles.
Main Outcome Measure(S):
Live birth.
Result(S):
Increasing male age was associated with semen parameters including volume and motility; however, male age was not observed to have a statistically significant association with likelihood of live birth in donor cycles after adjustment for female recipient age.
Conclusion(S):
When treatment cycle number and female recipient age were taken into account, male age had no significant association with pregnancy outcomes in assisted reproductive technology donor cycles in this study population.
Related Concept Videos
Infertility in Males
Oogenesis
Spermatogenesis
Infertility in Females
Endometriosis, a condition characterized by abnormal growth of endometrial...
Menopause
The Y Chromosome Determines Maleness
Evolution
Around 300 million years ago, the two sex chromosomes diverged from two identical autosomal chromosomes. Over time, the Y chromosome has lost most of its genes, shrinking in size. Today,...

